Prevalence of substance use disorders among patients with systemic lupus erythematous and major depressive disorder

Background Major depressive disorder (MDD) has a higher prevalence among patients with systemic lupus erythematous (SLE). Patients SLE struggle stressors such as social stigma and reduced employment. Furthermore, substance use disorders (SUD) are strongly associated MDD. Objectives This research investigated whether comorbid MDD is an increased of SUD diagnoses. Rates various diagnoses were compared SLE. Methods was retrospective comparison study the medical record. All data extracted from I2B2, deidentified dataset academic hospital in urban setting. Upon stratifying into two groups or without MDD, chi-squared test comparing completed. An additional analysis stratified completed to compare SUD. Results more likely have tobacco, alcohol, opioid disorders, others. The most common tobacco (prevalence 59.94%). diagnosis not rates diagnosis. However, diagnosed Conclusions demonstrates consistently rate versus alone. both when Our limited by its does include treatment depression on For clinicians who take care SLE, they should be screened.